Jonathan Taylor vs Miles Sanders: Who Should You Start?
The numbers tell a clear story here. Jonathan Taylor put up 20.0 fantasy points per game for the Indianapolis Colts in 2025, while Miles Sanders managed 5.7 across 4 games with the Dallas Cowboys. A 14.3-point weekly edge is substantial at the running back position.
Jonathan Taylor carries a 14.3-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Jonathan Taylor is the receiving back in this matchup, turning 46 targets into 378 yards, while Miles Sanders profiles as a more traditional rusher with 117 rushing yards and 1 touchdowns. In PPR and half-PPR formats Jonathan Taylor carries the higher weekly floor. In standard leagues the gap tightens considerably.
Bye weeks matter for roster construction: Jonathan Taylor sits Week 11 while Miles Sanders is off Week 10. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.
