Joe Mixon vs Kyle Monangai: Who Should You Start?
There is a real production gap between these two running backs. Joe Mixon (Houston Texans) averaged 16.5 PPG over 15 games in 2025, outscoring Kyle Monangai (Chicago Bears, 8.1 PPG) by 8.4 points per week. That separation would need a significant matchup swing to overcome.
A 8.4-PPG gap gives Joe Mixon the edge on paper, but paper does not account for Thursday night matchups, weather games, or a star defender returning from injury. The real question is not who was better in 2025, but who is the better start this specific week.
Both profile as early-down workhorses. Joe Mixon ran for 1165 yards and 11 touchdowns; Kyle Monangai posted 783 and 5. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: Joe Mixon is off Week 14 and Kyle Monangai Week 5. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
