Cam Skattebo vs Joe Mixon: Who Should You Start?
Deciding between Cam Skattebo and Joe Mixon is a common lineup dilemma for fantasy managers. The New York Giants running back put up 14.5 PPG in 2025 over 8 games; Joe Mixon of the Houston Texans averaged 16.5 in 15. A 2.0-point margin that could shift on any given week.
The per-game difference of 2.0 points favors Joe Mixon, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Both profile as early-down workhorses. Cam Skattebo ran for 410 yards and 5 touchdowns; Joe Mixon posted 1165 and 11. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
Both share a Week 14 bye, which matters for roster construction. If you are stacking running backs this deep on your bench, plan your replacement running back early.
