Head to Head

Updated May 14, 2026 from live stats

Amon-Ra St. Brown vs James Cook

Fantasy Football Comparison for the 2026 NFL Season

The Bottom Line

James Cook is the better fantasy play this season.

Cross-position decisions depend on league format. In half-PPR, James Cook (16.8 PPG) is the higher-floor play. Amon-Ra St. Brown (15.6 PPG) could win a specific week on touchdown variance. For FLEX spots, lean toward the player with the softer defensive matchup that week rather than defaulting to season averages.

Low confidence: the production gap is narrow enough that weekly context matters more than the season line.

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WRDetroit Lions#4

Amon-Ra St. Brown

PPG

15.6

Games

Rec

117

Rec Yds

1,401

Rec TDs

Targets

172

Bye

Week 8

RBBuffalo Bills#6PPG LEADER

James Cook

PPG

16.8

Games

Rush Yds

1,621

Rush TDs

Rec

Rec Yds

291

Bye

Week 7

The Edge Chart

Amon-Ra St. Brown

James Cook

Head to Head

15.6 PPG16.8 PPG

17 GP17 GP

Bye: Week 8Bye: Week 7

Fantasy Tiers

Amon-Ra St. Brown: Tier 1 (Elite) WR (ranked #4 at the position). James Cook: Tier 2 (Strong Starter) RB (ranked #6 at the position). Comparing across positions, raw PPG is less useful than positional scarcity. A Tier 1 (Elite) WR is harder to replace on waivers than a Tier 2 (Strong Starter) RB in most league formats.

Amon-Ra St. Brown vs James Cook: Who Should You Start?

Comparing Amon-Ra St. Brown (WR, Detroit Lions) against James Cook (RB, Buffalo Bills) means weighing two different roles in your fantasy lineup. Amon-Ra St. Brown averaged 15.6 PPG in 2025 over 17 games, while James Cook posted 16.8 PPG across 17 games.

Cross-position FLEX decisions cannot be made on PPG alone. Positional scarcity, matchup quality, floor versus ceiling, and league scoring format all shift the answer. A 14 PPG tight end in a thin TE week is often worth more than a 16 PPG receiver in a deep WR week, because the opportunity cost on the waiver wire is wildly different.

DraftCall's AI engine weighs all of these signals and returns a verdict with clear reasoning, so you are not cross-referencing four different rankings tabs on a Sunday morning.

Amon-Ra St. Brown has his bye in Week 8, James Cook in Week 7. Plan your FLEX rotation around those weeks, especially if either player is anchoring your roster.

Trade Value + Dynasty Outlook

Both are in a similar trade value range. A straight swap would be fair in most leagues, with the tiebreaker going to whichever manager values schedule or bye week more. Dynasty outlook: Amon-Ra St. Brown (age 26) is in the middle of his productive window. Stable dynasty value. James Cook (age 26) is approaching the age where RB production historically drops. Sell-high window is open.

Did You Know?

•James Cook outscored Amon-Ra St. Brown by a projected 20 total fantasy points over a full 17-game season.
•James Cook scored 14 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.
•Amon-Ra St. Brown saw 172 targets in 2025. Target volume is the single strongest predictor of weekly PPR production at the wide receiver position.

Detailed Stat Breakdown▾

StatBrownCook

PPG (Half-PPR)15.616.8

Games Played1717

Total Fantasy Pts (est.)265286

Rushing Yards91,621

Rush Yds/Game0.595.4

Rushing TDs012

Receptions11733

Receiving Yards1,401291

Targets17240

Total TDs1114

Age2626

Experience4 yrs3 yrs

Bye WeekWeek 8Week 7

Summary

James Cook outscored Amon-Ra St. Brown by 1.2 PPG in 2025 (16.8 to 15.6). That production gap is the baseline, but weekly context shifts the answer. DraftCall analyzes matchup difficulty, scoring trends, and health data to deliver a clear start or sit recommendation backed by real reasoning.

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Frequently Asked Questions

Should I start Amon-Ra St. Brown or James Cook in fantasy football?▾

Based on 2025 season averages, James Cook has the edge at 16.8 PPG compared to Amon-Ra St. Brown's 15.6 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Amon-Ra St. Brown and James Cook average in 2025?▾

Amon-Ra St. Brown averaged 15.6 fantasy points per game (half-PPR) across 17 games in 2025. James Cook averaged 16.8 PPG over 17 games. That is a difference of 1.2 points per game.

When are Amon-Ra St. Brown and James Cook's bye weeks in 2026?▾

Amon-Ra St. Brown (DET) has a bye in Week 8, and James Cook (BUF) has a bye in Week 7. Plan your roster accordingly if you are carrying both players.