Chase Brown vs Joe Mixon: Who Should You Start?
If you are choosing between Chase Brown and Joe Mixon for your lineup, you are not alone. Chase Brown finished the 2025 season at 14.6 PPG for the Cincinnati Bengals (17 games), and Joe Mixon averaged 16.5 for the Houston Texans (15 games).
That 1.9-point weekly advantage for Joe Mixon is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Chase Brown is the receiving back in this matchup, turning 69 targets into 437 yards, while Joe Mixon profiles as a more traditional rusher with 1165 rushing yards and 11 touchdowns. In PPR and half-PPR formats Chase Brown carries the higher weekly floor. In standard leagues the gap tightens considerably.
One scheduling note: Chase Brown is off Week 10 and Joe Mixon Week 14. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
